NBR1 is a new PB1 signaling adapter in Th2 differentiation and allergic airway inflammation in vivo
نویسندگان
چکیده
Table SI. Splenic immune cell populations unchanged in conditional NBR1-deficient mice CD4 CD8 B220 NK1.1 CD11b + F4/80 CD11c F4/80 NBR1fl/fl 17.6 ± 1.0 13.9 ± 0.7 59.7 ± 2.1 3.7 ± 0.7 5.9 ± 0.5 4.1 ± 0.3 NBR1fl/fl CreOX40 17.9 ± 0.8 14.6 ± 0.4 60.0 ± 0.9 4.3 ± 0.5 5.9 ± 0.6 4.8 ± 0.6 Single-cell suspension from spleen were stained by FACS. Percentages (Means ± SE) of positive cells gated on lymphocytes are shown (n = 23 per group).
منابع مشابه
NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.
Allergic airway inflammation is a disease in which T helper 2 (Th2) cells have a critical function. The molecular mechanisms controlling Th2 differentiation and function are of paramount importance in biology and immunology. Recently, a network of PB1-containing adapters and kinases has been shown to be essential in this process owing to its function in regulating cell polarity and the activati...
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